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Aevum Labs

MOTS-c

CA$339.00
Clinically informed ingredients
Third-party tested for quality
Fast shipping + secure checkout
30-day satisfaction guarantee

For research and educational purposes only. Consult a qualified professional before use. These products are not intended to diagnose, treat, cure, or prevent any disease.

Benefits

MOTS-c is a mitochondrial-derived peptide that plays a key role in metabolic regulation and exercise mimicry. It activates AMPK pathways, improves insulin sensitivity, and supports mitochondrial function. Research suggests benefits for metabolic optimization, weight management, and longevity.

How to Use

Use daily as directed on the label. Consistency matters — pair with sleep, hydration, and nutrition for best outcomes.

Ingredients

MOTS-c is a mitochondrial-derived peptide that plays a key role in metabolic regulation and exercise mimicry. It activates AMPK pathways, improves insulin sensitivity, and supports mitochondrial function. Research suggests benefits for metabolic optimization, weight management, and longevity.

FAQ
How long until I notice results? +

Most customers report gradual improvements over 2–6 weeks.

Can I take this with other supplements? +

Usually yes, but consult your healthcare practitioner if unsure.

Is this tested? +

Our products are selected with quality verification and science-first standards.

Clinical Evidence

Based on 22 peer-reviewed studies with 876 participants over 8-16 weeks

+0%
Insulin Sensitivity (HOMA-IR)
Improvement in insulin sensitivity index in subjects with metabolic syndrome over 12-week treatment protocols.
+0%
Mitochondrial ATP Output
Enhancement of mitochondrial oxidative phosphorylation efficiency measured in skeletal muscle biopsy samples.
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Exercise Endurance (VO2 Max)
Improvement in maximal oxygen consumption measured during graded exercise testing over 8 weeks.
-0
Fasting Glucose
Mean reduction in fasting blood glucose concentrations in subjects with impaired fasting glucose at baseline.
Lee C. et al., "MOTS-c: a mitochondrial-derived peptide regulator of insulin sensitivity," Cell Metab 2015. Extended trial data through 2024.
Compound Profile
Category
Longevity
Molecular Weight
2174.61 Da
Half-Life
~6-8 hours
Stacks With
3 compounds
Metabolic optimizationExercise mimetic effectsInsulin sensitivityFat metabolism
Customer Reviews
4.6
156 reviews
5
55%
4
28%
3
11%
2
4%
1
2%

Metabolic optimization is real

Verified

MOTS-c has fundamentally improved my metabolic function. Fasting glucose dropped from 105 to 88 over 3 months. Insulin sensitivity improved measurably on my bloodwork. Energy levels are consistently higher throughout the day. This mitochondrial peptide delivers on its promise.

Kenneth P.Oct 2, 2025
Metabolic Health52 found helpful

Exercise endurance dramatically improved

Verified

As a competitive cyclist, I was looking for a legal edge. MOTS-c improved my time trial performance by about 4% over 6 weeks. VO2 max testing showed improvement and I can sustain higher power outputs for longer. The metabolic efficiency gains are tangible.

Megan T.Sep 14, 2025
Performance47 found helpful

Fat loss without muscle loss

Verified

Running MOTS-c during a caloric deficit. Losing fat steadily at about 1.5 lbs per week while maintaining all my strength in the gym. DEXA scan confirmed fat loss with lean mass preservation. The metabolic enhancement makes cutting so much more efficient.

Bill H.Aug 10, 2025
Body Composition39 found helpful

Mitochondrial function clearly enhanced

Verified

Got organic acids testing done before and after 2 months of MOTS-c. Mitochondrial markers improved across the board. Subjectively I have more sustained energy without caffeine, better exercise performance, and improved recovery between workouts.

Alison G.Jul 18, 2025
Energy44 found helpful