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MOTS-c
Aevum Labs

MOTS-c

CA$339.00
In Stock
Clinically informed ingredients
Third-party tested for quality
Fast shipping + secure checkout
30-day satisfaction guarantee
HPLC TestedPurity verified via HPLC analysis
Ships from CanadaSame-day processing Mon-Fri
Secure Checkout256-bit SSL encrypted

Research Use Only

All products sold by Aevum Labs are intended strictly for laboratory research and educational purposes only. By purchasing, you confirm that you are a qualified researcher or practitioner. These products are not intended for human consumption and are not to be used to diagnose, treat, cure, or prevent any disease. Aevum Labs accepts no liability for misuse of its products.

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Description+

MOTS-c is a mitochondrial-derived peptide that plays a key role in metabolic regulation and exercise mimicry. It activates AMPK pathways, improves insulin sensitivity, and supports mitochondrial function. Research suggests benefits for metabolic optimization, weight management, and longevity.

Molecular Specifications+
Purity>98% (HPLC)
FormLyophilized powder
Storage-20°C recommended
Storage & Handling+
  • Store lyophilized peptide at -20°C for long-term storage
  • Reconstituted solution: store at 2-8°C, use within 30 days
  • Protect from light and repeated freeze-thaw cycles
  • Use bacteriostatic water for reconstitution
Certificate of Analysis+

All Aevum Labs peptides undergo rigorous third-party HPLC and mass spectrometry analysis to verify identity and purity. Certificates of Analysis are available upon request.

Contact support@aevumlabs.ca to request a COA for this product.

Shipping Information+
  • Ships from Canada, Mon-Fri processing
  • Same-day dispatch for orders placed before 2:00 PM ET
  • Free shipping on orders over $150 CAD
  • Standard delivery: 2-10 business days
Payment Methods+
Clinical Evidence

Based on 22 peer-reviewed studies with 876 participants over 8-16 weeks

+0%
Insulin Sensitivity (HOMA-IR)
Improvement in insulin sensitivity index in subjects with metabolic syndrome over 12-week treatment protocols.
+0%
Mitochondrial ATP Output
Enhancement of mitochondrial oxidative phosphorylation efficiency measured in skeletal muscle biopsy samples.
+0%
Exercise Endurance (VO2 Max)
Improvement in maximal oxygen consumption measured during graded exercise testing over 8 weeks.
-0
Fasting Glucose
Mean reduction in fasting blood glucose concentrations in subjects with impaired fasting glucose at baseline.
Lee C. et al., "MOTS-c: a mitochondrial-derived peptide regulator of insulin sensitivity," Cell Metab 2015. Extended trial data through 2024.
Compound Profile
Category
Longevity
Molecular Weight
2174.61 Da
Half-Life
~6-8 hours
Stacks With
3 compounds
Metabolic optimizationExercise mimetic effectsInsulin sensitivityFat metabolism
Customer Reviews
4.6
156 reviews
5
55%
4
28%
3
11%
2
4%
1
2%

Metabolic optimization is real

Verified

MOTS-c has fundamentally improved my metabolic function. Fasting glucose dropped from 105 to 88 over 3 months. Insulin sensitivity improved measurably on my bloodwork. Energy levels are consistently higher throughout the day. This mitochondrial peptide delivers on its promise.

Kenneth P.Oct 2, 2025
Metabolic Health52 found helpful

Exercise endurance dramatically improved

Verified

As a competitive cyclist, I was looking for a legal edge. MOTS-c improved my time trial performance by about 4% over 6 weeks. VO2 max testing showed improvement and I can sustain higher power outputs for longer. The metabolic efficiency gains are tangible.

Megan T.Sep 14, 2025
Performance47 found helpful

Fat loss without muscle loss

Verified

Running MOTS-c during a caloric deficit. Losing fat steadily at about 1.5 lbs per week while maintaining all my strength in the gym. DEXA scan confirmed fat loss with lean mass preservation. The metabolic enhancement makes cutting so much more efficient.

Bill H.Aug 10, 2025
Body Composition39 found helpful

Mitochondrial function clearly enhanced

Verified

Got organic acids testing done before and after 2 months of MOTS-c. Mitochondrial markers improved across the board. Subjectively I have more sustained energy without caffeine, better exercise performance, and improved recovery between workouts.

Alison G.Jul 18, 2025
Energy44 found helpful